Lausanne cohort 65+ study (Lc65+)

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The Lausanne cohort 65+ (Lc65+) study is a research platform on aging aimed at better understanding frailty from the age of 65 in the general population. It consists of four samples of approximately 1,500 participants each, representative of the population of the city of Lausanne born before, during, at the end of World War II, and in the middle of the baby-boom generation. These four samples were enrolled successively at the same age of 65–70 years in 2004 (birth years 1934–1938), 2009 (1939-1943), 2014 (1944-1948), and 2024 (1954-1958).

The analytical framework of the study is centered on a multidimensional investigation of frailty, including its clinical manifestations, underlying risk factors, and its broader implications for health status, quality of life, and healthcare utilization. From a public health standpoint, the overarching objective is to foster healthy aging by enabling the early identification of frailty and implementing strategies to mitigate its adverse outcomes.

Website: https://www.lc65plus.ch/en

Start date:
Project Leader / Principal Investigator HENCHOZ Yves
Funders Fondation Leenaards Fond national suisse (FNS) Swiss Personalized Health Network (SPHN) Fondation Esther Locher-Gurtner Loterie romande Ville de Lausanne VD - Direction générale de la santé (DGS) Centre hospitalier universitaire vaudois (CHUV) Policlinique médicale universitaire (PMU-Unisanté) Faculté de biologie et de médecine (FBM), Université de Lausanne (UNIL)